(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol - Names and Identifiers
Name | (1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol
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Synonyms | (1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-... (1r,2s)-1-[(3,5-di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol (1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol (1R,2S)-1-((3,5-Di-tert-butyl-2-hydroxybenzylidene)amino)-2,3-dihydro-1H-inden-2-ol 1H-Inden-2-ol, 1-[[[3,5-bis(1,1-dimethylethyl)-2-hydroxyphenyl]methylene]amino]-2,3-dihydro-, (1R,2S)-
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CAS | 275374-67-9
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InChI | InChI=1/C24H31NO2/c1-23(2,3)17-11-16(22(27)19(13-17)24(4,5)6)14-25-21-18-10-8-7-9-15(18)12-20(21)26/h7-11,13-14,20-21,25-26H,12H2,1-6H3/b16-14-/t20-,21+/m0/s1 |
(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol - Physico-chemical Properties
Molecular Formula | C24H31NO2
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Molar Mass | 365.51 |
Melting Point | 128-133°C(lit.) |
Refractive Index | 1.584 |
(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol - Risk and Safety
Hazard Symbols | Xi - Irritant

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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
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WGK Germany | 3 |
(1R,2S)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol - Introduction
(1R,2S)-1-[(3,) amino]-2-indanol is an organic compound with the molecular formula C25H33NO2. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
(1R,2s)-1-[(3,) amino]-2-indanol is a solid substance, usually in the form of yellow crystals or crystalline powder. It has a high melting point and boiling point, and is stable at room temperature. The compound has good solubility in organic solvents.
Use:
(1R,2s)-1-[(3,) amino]-2-indanol has some applications in the pharmaceutical field. Due to its structure containing an indene ring and a hydroxybenzenediamine group, the compound acts as an antioxidant and free radical scavenger. In addition, it has certain anti-inflammatory and anti-tumor properties. In the process of research and development of new drugs, the compound is often used as an intermediate or basic structure.
Method:
The preparation method of (1R,2s)-1-[(3,) amino]-2-indanol usually involves a multi-step reaction. A common synthetic route is through the amidation reaction of benzophenol, cyclization with appropriate methylene Amine, followed by reduction, and finally through indanol synthesis to obtain the target compound.
Safety Information:
The safety of (1R,2s)-1-[(3, 3) amino]-2-indanol has not been fully studied. In general, however, regular laboratory safety measures should be followed when handling and storing chemicals. This includes wearing appropriate personal protective equipment (such as gloves, glasses, laboratory coats, etc.) and avoiding contact with skin and eyes. In addition, the experiment should be carried out in a well-ventilated place and avoid contact with oxidants and combustibles. Seek immediate medical help if ingestion or exposure to the compound is accidental.
Last Update:2024-04-09 21:54:55